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eDarkTrends : Monitoring Cryptomarkets to Identify Emerging Trends of Illicit Synthetic Opioids Use is an inter-disciplinary project between the Ohio Center of Excellence in Knowledge-enabled Computing (Kno.e.sis) and the Center for Interventions, Treatment and Addictions Research (CITAR) at Wright State University developed to monitor illicit online transactions of several illicit synthetic opioids in dark web.


Principal Investigators: Francois Lamy , Amit P. Sheth
Co-Investigators: Raminta Daniulaityte, Robert Carlson, Ramzi Nahhas Dr. Barratt
Graduate Students: Usha Lokala, Farahnaz Golroo
Softwrare Engineers: Mike Partin


The cause of this project is to design effective and responsive prevention and policy measures as public health professionals require timely and reliable information on trends in illicit synthetic opioid supply and availability. Monitoring cryptomarkets offers a valuable source of information for epidemiological surveillance by providing timely data regarding emerging substances and product form (e.g., powder, e-liquid). However, the frequent introduction of unclassified molecules combined with the opacity of cryptomarkets constitutes a challenge for traditional epidemiological surveillance systems. The National Forensic Laboratory Information System (NFLIS) provides crucial information about drugs seized by law enforcement across the U.S, but it is time lagged. The National Drug Early Warning System (NDEWS) collects timely data from sentinel sites and social media sources, but it is limited to data as displayed on the public side of the "Surface" Web. Prior studies, as well as several governmental agencies, have monitored the Surface Web to identify emerging cryptomarkets to evaluate volumes of substances being supplied, drug prices, number of sellers, seller revenue, number of cryptomarkets, and country specifics. However, there is no epidemiological surveillance system based on cryptomarket data that is oriented toward identifying emerging illicit synthetic opioids or monitoring changes in Darknet supply and marketing trends over time. Analysis of cryptomarket data could provide a powerful new tool for epidemiological surveillance enhancing the capacities of early warning systems to capture changes in the illicit synthetic opioid supply and availability.

Research Plan

The proposed study is multidisciplinary which builds on an existing, strong multidisciplinary collaboration integrating the fields of drug abuse research and computer sciences. This research answers why monitor illicit synthetic opiods in dark net cryptomarkets and why to employ advanced information processing techniques. The architecture and the sample data extracted is shown in Figure 1 and 2 respectively.

Figure 1. eDarkTrends Overall Architecture and Research Plan
Figure 2. Example of data extracted using eDarkTrends

Research Innovation

The proposed study is highly innovative in the following ways: 1) eDarkTrends will be the first system to track and describe trends in illicit synthetic opioid supply and marketing on three cryptomarkets over a 20-month period for epidemiological monitoring and early warning network; 2) It will also be the first system created specifically for U.S-focused cryptomarket monitoring of illicit synthetic opioids supply and availability trends; 3) eDarkTrends proposes significant methodological innovation because it will be the first to develop and apply advanced information processing techniques for more rapid and efficient drug-related information extraction from cryptomarket data sources; 4) It will also be the first to develop and deploy computational information processing techniques to automatically identify emerging or previously unknown illicit synthetic opioid compounds or products forms as soon as they appear on cryptomarkets. Such computational techniques will bring significant innovation to web-based research in general because most prior methods were typically based on manual coding and lacked the ability to automatically identify yet unknown substances or known substances but emerging as substance of abuse, drug forms or drug combinations. It also has the potential to bring innovative methods to crawl cryptomarkets and advanced entity spotting techniques to Web-based research methods in other areas of public health.

Specific Aims

Submitted in response to PAR-16-055, the overall goals of this time-sensitive R21 are to harness cryptomarket data to conduct surveillance of the illicit synthetic opioid markets availability trends over time, and identify new substances as they emerge on cryptomarkets. The Specific Aims are to:

  • Aim 1: Develop a semi-automated system, eDarkTrends, to collect and process data about illicit synthetic opioids supplied on cryptomarkets.
  • Aim 2: Deploy eDarkTrends to:
    • Aim 2.a: Describe and monitor U.S-based supply trends of illicit synthetic opioids on cryptomarkets (e.g., trends in availability of non-pharmaceutical fentanyl analogs, U-47700, MT-45), including types of illicit synthetic opioids, prices, advertised purity, dosage, product forms, quantity supplied, and drug combinations;
    • Aim 2.b: Identify new illicit synthetic opioid substances and product forms soon after they appear on cryptomarkets.


  • Grant Number: 1 R21DA044518
  • Principal Investigators: Francois Lamy Amit P. Sheth (Kno.e.sis, Wright State University)
  • Project Title: eDarkTrends: Monitoring Cryptomarkets to Identify Emerging Trends of Illicit Synthetic Opioids Use
  • Timeline: 08/15/2017 – 07/31/2019
  • Award Amount: $223,715

Concurrent Projects at Kno.e.sis

Prior relevant Projects


Figure 3. eDarkTrends update: New synthetic opioids, MPF-47,700, U-4TDP, U-48,800, U-49,900, and U-50,488 identified on two cryptomarkets.

Social Media

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Usha Lokala